A Machine Learning Approach for Chronic Heart Failure Diagnosis.
Dafni K Plati1, Evanthia E Tripoliti1, Aris Bechlioulis2
1Department of Biomedical Research, Institute of Molecular Biology and Biotechnology, FORTH, 45110 Ioannina, Greece.
Diagnostics (Basel, Switzerland)
|October 23, 2021
Summary
Machine learning (ML) accurately diagnoses chronic heart failure (HF) using clinical, echocardiogram, and lab data. Models achieved over 91% accuracy, demonstrating the effectiveness of ML in HF diagnostics.
Area of Science:
- Medical Informatics
- Artificial Intelligence in Medicine
- Cardiology
Background:
- Chronic heart failure (HF) diagnosis poses clinical challenges.
- Machine learning (ML) offers potential for improving diagnostic accuracy.
Purpose of the Study:
- To evaluate ML approaches for diagnosing chronic heart failure (HF).
- To assess the diagnostic value of combining clinical, echocardiogram, and laboratory features.
- To investigate the incremental contribution of each feature category.
Main Methods:
- Developed ML models using feature selection, class imbalance handling, and classification.
- Utilized a dataset of 422 subjects.
- Simulated clinical diagnostic procedures by testing various feature combinations.
Main Results:
- Achieved high diagnostic accuracy (91.23%) for HF when using all feature categories.
- Demonstrated high sensitivity (93.83%) and specificity (89.62%).
- Maintained strong performance even when using single feature types.
Conclusions:
- ML models are effective for diagnosing chronic heart failure (HF).
- Combining diverse data types (clinical, echocardiogram, laboratory) enhances diagnostic performance.
- Individual feature types also provide valuable diagnostic information.
Related Concept Videos
Heart Failure IV: Classification and Diagnostic Evaluation
73
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
73
Heart Failure V: Medical Management
49
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
49
Pathophysiology of Heart Failure
2.0K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
2.0K
Cardiomyopathy V: Interprofessional Care
65
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
65
Heart Failure II: Pathophysiology
101
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
101
Heart Failure I: Introduction
131
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
131

