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Histology of the Uterus

Histology of the Uterus

The uterine wall consists of three histological layers: the perimetrium, myometrium, and endometrium. The outermost perimetrium is a thin, serous membrane connected with the broad ligament on the sides, which helps anchor the uterus in the pelvic cavity. The thickest layer, myometrium, is mainly made up of smooth muscle tissue bundles. Its contractions are vital in facilitating the expulsion of the uterine lining, fetus, and placenta during menstruation and childbirth.
The endometrium is the...

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Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

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Ectopic Endometrium: The Pathologist's Perspective.

Alessandra Camboni^1,2, Etienne Marbaix^2,3

¹Gynecology Research Unit, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain, 1200 Brussels, Belgium.

International Journal of Molecular Sciences

|October 23, 2021

Summary

Endometriosis and adenomyosis are common conditions involving ectopic endometrium that cause pain and infertility. Their exact causes remain unclear despite extensive research, highlighting the need for better understanding and classification.

Keywords:

adenomyosis endometrial cancer endometriosis histological diagnosis ovarian cancer pathological classification pathology

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Area of Science:

Gynecology
Pathology

Background:

Endometriosis and adenomyosis are frequent, related diseases characterized by ectopic endometrial tissue.
These benign conditions significantly impact women's quality of life through pain and infertility, and are associated with increased gynecological cancer risk.

Purpose of the Study:

To review the pathological aspects of endometriosis and adenomyosis.
To provide a historical perspective and incorporate recent findings on these complex diseases.

Main Methods:

Literature review focusing on pathological descriptions, classification attempts, and pathogenic theories.
Analysis of historical data and newly reported scientific information.

Main Results:

Multiple theories exist for the pathogenesis of endometriosis and adenomyosis, but none fully explain all manifestations.
Lack of standardized diagnostic criteria in pathology hinders research and classification.

Conclusions:

The precise pathogeneses of endometriosis and adenomyosis remain incompletely understood.
A comprehensive review of pathological features, from historical context to current data, is crucial for advancing the study and classification of these disorders.