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Updated: Oct 16, 2025

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
Published on: September 8, 2023
Engaging Patients with Late-Stage Non-Small Cell Lung Cancer in Shared Decision Making about Treatment
Ronald E Myers1, Shailesh M Advani2, Pamela Myers1
1Division of Population Science, Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.
A new decision support intervention (DSI) helps late-stage non-small cell lung cancer (NSCLC) patients understand treatment options and make informed choices. The DSI increased patient awareness and decreased decision-making uncertainty.
Area of Science:
- Oncology
- Medical Informatics
- Patient Engagement
Background:
- Limited treatment decision support interventions (DSIs) exist for patients with late-stage non-small cell lung cancer (NSCLC).
- Shared decision making (SDM) is crucial for these patients to navigate complex treatment choices.
Purpose of the Study:
- To design and evaluate a novel DSI for NSCLC patients to facilitate SDM.
- To assess the DSI's impact on patient awareness, preferences, and decision-making uncertainty.
Main Methods:
- Developed a DSI comprising care plan cards and a patient preference tool.
- Gathered feedback from clinicians and patients through interviews.
- Trained oncology nurse educators for DSI implementation.
- Pilot tested the DSI with five NSCLC patients before treatment discussions.
Main Results:
- DSI use correlated with increased patient awareness of treatment options, benefits, and risks.
- Patient concerns regarding treatment costs and decision-making uncertainty were reduced.
- All pilot study participants successfully expressed a treatment preference.
Conclusions:
- The novel DSI shows promise in enhancing patient engagement and SDM for NSCLC.
- Further randomized controlled trials are necessary to confirm feasibility and clinical efficacy.
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