Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polarization-Sensitive Holotomography for Multidimensional Label-Free Imaging and Characterization of Lipid Droplets in Cancer Cells.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same author

Near-Field Optical Nanopatterning of Graphene.

Small science·2025
Same author

TGF-β1-mediated downregulation of L1CAM in pancreatic ductal adenocarcinoma drives upregulation of collagen 17A1 and MMP2, facilitating tumor invasiveness and metastasis.

Cell death & disease·2025
Same author

Hybrid Biosilica Nanoparticles for in-vivo Targeted Inhibition of Colorectal Cancer Growth and Label-Free Imaging.

International journal of nanomedicine·2024
Same author

Correlative Raman Imaging: Development and Cancer Applications.

Biosensors·2024
Same author

Towards a New Generation of Hormone Therapies: Design, Synthesis and Biological Evaluation of Novel 1,2,3-Triazoles as Estrogen-Positive Breast Cancer Therapeutics and Non-Steroidal Aromatase Inhibitors.

Pharmaceuticals (Basel, Switzerland)·2024
Same journal

RETRACTED: Al-Hussain et al. Application of New Sodium Vinyl Sulfonate-co-2-Acrylamido-2-me[thylpropane Sulfonic Acid Sodium Salt-Magnetite Cryogel Nanocomposites for Fast Methylene Blue Removal from Industrial Waste Water. <i>Nanomaterials</i> 2018, <i>8</i>, 878.

Nanomaterials (Basel, Switzerland)·2026
Same journal

Correction: Jiang et al. Methods for Obtaining One Single Larmor Frequency, Either <i>v</i><sub>1</sub> or <i>v</i><sub>2</sub>, in the Coherent Spin Dynamics of Colloidal Quantum Dots. <i>Nanomaterials</i> 2023, <i>13</i>, 2006.

Nanomaterials (Basel, Switzerland)·2026
Same journal

Correction: Ekman et al. Synthesis, Characterization, and Adsorption Properties of Nitrogen-Doped Nanoporous Biochar: Efficient Removal of Reactive Orange 16 Dye and Colorful Effluents. <i>Nanomaterials</i> 2023, <i>13</i>, 2045.

Nanomaterials (Basel, Switzerland)·2026
Same journal

Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub>-Based Materials and Coatings for De-Icing and Defogging of Wind Turbine Blades: Materials Basis, Structural Design, Engineering Integration, and Future Opportunities.

Nanomaterials (Basel, Switzerland)·2026
Same journal

Influence of the Ripeness Stages of the Precursors on the Optical Characteristics of Carbon Dots Obtained from Valencia Orange Peels (<i>Citrus sinensis</i> L. Osbeck) by Hydrothermal Synthesis.

Nanomaterials (Basel, Switzerland)·2026
Same journal

Insights into ALD Growth of Al-Based Dielectric Stack on 4H-SiC.

Nanomaterials (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Oct 15, 2025

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.8K

Biosensing Using SERS Active Gold Nanostructures.

Gour Mohan Das1, Stefano Managò1, Maria Mangini1

  • 1Laboratory of Biophotonics and Advanced Microscopy, Second Unit, Institute of Experimental Endocrinology and Oncology "G. Salvatore" (IEOS), National Research Council (CNR), Via P. Castellino 111, 80131 Naples, Italy.

Nanomaterials (Basel, Switzerland)
|October 23, 2021
PubMed
Summary
This summary is machine-generated.

Surface-enhanced Raman spectroscopy (SERS) offers high sensitivity and fingerprint recognition for biosensing. This review covers SERS mechanisms, substrates, performance factors, and biomedical applications.

Keywords:
SERSbiosensinggold nanoparticles

More Related Videos

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.7K
Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
06:19

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Published on: June 23, 2022

2.7K

Related Experiment Videos

Last Updated: Oct 15, 2025

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.8K
Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.7K
Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
06:19

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations

Published on: June 23, 2022

2.7K

Area of Science:

  • Analytical Chemistry
  • Biomedical Engineering
  • Spectroscopy

Background:

  • Surface-enhanced Raman spectroscopy (SERS) is a valuable technique for biosensing.
  • Its advantages include fingerprint recognition, high sensitivity, multiplex detection, and biocompatibility.

Purpose of the Study:

  • To provide a comprehensive overview of SERS for biomedical and biosensing applications.
  • To discuss SERS mechanisms, substrates, characterization, and applications.

Main Methods:

  • Review of electromagnetic and chemical enhancement mechanisms.
  • Illustration of various SERS substrates and fabrication methods, emphasizing gold nanostructures.
  • Analysis of SERS sensor performance factors: sensitivity, reproducibility, stability, configuration, and nanotoxicity.

Main Results:

  • Detailed explanation of SERS amplification mechanisms.
  • Comparison of different substrate types and fabrication techniques.
  • In-depth analysis of critical SERS sensor performance metrics.
  • Presentation of diverse biomedical applications.

Conclusions:

  • SERS is a powerful and versatile tool for advanced biosensing and biomedical diagnostics.
  • Understanding SERS mechanisms, substrate design, and performance evaluation is crucial for successful application development.