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Updated: Oct 15, 2025
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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
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Percutaneous management of paravalvular leaks
Joel P Giblett1, Lynne K Williams2, Narain Moorjani3
1Liverpool Centre for Cardiovascular Science, Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool, UK.
Heart (British Cardiac Society)
|October 23, 2021
Summary
Percutaneous closure of paravalvular leak (PVL) offers comparable success to surgery with reduced short-term mortality. This minimally invasive option provides quicker recovery, making it attractive for high-risk patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Paravalvular leak (PVL) is a serious complication after valve replacement surgery.
- Severe symptomatic PVL often requires intervention, but many patients are high-risk for repeat surgery.
Purpose of the Study:
- To review the current evidence comparing percutaneous closure with surgical repair for paravalvular leaks.
- To assess the safety, efficacy, and outcomes of percutaneous PVL closure.
Main Methods:
- Review of national registries and retrospective studies comparing surgical and percutaneous PVL repair.
- Analysis of technical success rates, mortality, and long-term outcomes.
Main Results:
- Percutaneous closure demonstrates high technical success rates, comparable to surgical repair.
- Studies show reduced short-term mortality and similar long-term outcomes for percutaneous closure.
- Percutaneous repair is less invasive with a faster recovery period.
Conclusions:
- Percutaneous closure is a viable and attractive option for managing paravalvular leaks, especially in high-risk patients.
- Further prospective studies are needed to solidify the role of percutaneous techniques in PVL management.
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