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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
Cardiac involvement in the long-term implications of COVID-19
Benjamin A Satterfield1, Deepak L Bhatt2, Bernard J Gersh3
1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Insights
Long COVID survivors may face lasting cardiovascular issues. New prospective studies are crucial now to understand and manage these long-term heart complications in post-COVID syndrome.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic has caused significant acute illness and death globally.
- Vaccine advancements offer hope, shifting focus towards managing long-term health consequences.
- Survivors of acute COVID-19 may experience persistent cardiovascular sequelae.
Purpose of the Study:
- To review current knowledge on cardiovascular complications in COVID-19 survivors.
- To identify critical research questions for understanding long-term cardiovascular effects.
- To emphasize the need for immediate prospective studies on this population.
Main Methods:
- This is a Perspectives article, synthesizing existing literature and expert opinion.
- It highlights known cardiovascular sequelae based on current research.
- It outlines future research directions and necessary methodologies.
Main Results:
- Cardiovascular sequelae are a significant concern in COVID-19 survivors.
- Specific long-term effects include myocarditis, arrhythmias, and thromboembolic events.
- The full spectrum and mechanisms of these complications require further investigation.
Conclusions:
- Prospective studies are urgently needed to monitor and understand cardiovascular health in COVID-19 survivors.
- Research should focus on identifying risk factors and developing mitigation strategies for post-acute COVID-19 syndrome.
- Adequate resources must be allocated to support long-term follow-up and research.
Abstract:
Throughout 2021, the medical and scientific communities have focused on managing the acute morbidity and mortality caused by the coronavirus disease 2019 (COVID-19) pandemic. With the approval of multiple vaccines, there is a light at the end of this dark tunnel and an opportunity to focus on the future, including managing the long-term sequelae in patients who have survived acute COVID-19. In this Perspectives article, we highlight what is known about the cardiovascular sequelae in survivors of COVID-19 and discuss important questions that need to be addressed in prospective studies to understand and mitigate these lasting cardiovascular consequences, including in post-acute COVID-19 syndrome. To provide the greatest benefit to these survivors, prospective studies should begin now, with resources made available to monitor and study this population in the coming years.
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