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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

519
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
519
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

641
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
641
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

228
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
228
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

409
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
409
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

267
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
267
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

981
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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Updated: Oct 15, 2025

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
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Hepatic tuberculosis masquerading as malignancy.

Aditya Kale1, Prachi S Patil2, Utkarsh Chhanchure1

  • 1Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital, Homi Bhabha National Institute (HBNI), Dr Ernest Borges road, Parel, Mumbai, Pin: 400012, India.

Hepatology International
|October 23, 2021
PubMed
Summary
This summary is machine-generated.

Hepatic tuberculosis (HTB) is a rare condition that often mimics liver cancer, leading to misdiagnosis. Early suspicion and antitubercular therapy (ATT) are crucial for effective treatment and avoiding unnecessary surgery.

Keywords:
Capsular retractionCaseation necrosisCholangiocarcinomaHepatic metastasisHepatic tuberculosisLanghan’s giant cellsMasqueraderTumor markers

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Area of Science:

  • Hepatology
  • Infectious Diseases
  • Radiology

Background:

  • Hepatic tuberculosis (HTB) is an uncommon manifestation of tuberculosis.
  • It frequently mimics malignant liver lesions, posing diagnostic challenges.

Purpose of the Study:

  • To analyze the clinical, radiological, and histopathological features of hepatic tuberculosis.
  • To highlight diagnostic challenges and emphasize the importance of early diagnosis to prevent misdiagnosis and unnecessary surgeries.

Main Methods:

  • Retrospective analysis of 43 confirmed cases of HTB over 10 years.
  • Review of clinical data, imaging (ultrasound, CT, MRI), and histopathology reports.

Main Results:

  • HTB presented with constitutional symptoms, abdominal pain, and hepatomegaly in a significant proportion of patients.
  • Radiological findings included hypoechoic (ultrasound) and hypodense (CT) lesions; calcifications and capsular retraction were uncommon.
  • Histopathology confirmed granulomatous inflammation with caseation necrosis in most cases; extrahepatic involvement was observed in 46.5%.

Conclusions:

  • Hepatic tuberculosis can present as a diagnostic challenge, often mimicking primary or secondary liver malignancies.
  • Multiphase CT findings like calcifications and pseudocapsule may aid in differentiation.
  • A high index of suspicion is essential for prompt diagnosis and initiation of antitubercular therapy (ATT), leading to favorable outcomes.