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Late-onset hematological complications post COVID-19: An emerging medical problem for the hematologist
Eleni Korompoki1, Maria Gavriatopoulou1, Despina Fotiou1
1Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Insights
This review details post-COVID-19 hematological disorders, including coagulopathy and thrombocytopenia. Hematologists play a key role in managing these long COVID-19 complications through laboratory monitoring and supportive care.
Area of Science:
- Hematology
- Immunology
- Infectious Diseases
Background:
- Coronavirus disease 19 (COVID-19) is a multisystemic illness.
- Persistent symptoms and late-onset complications, including hematological disorders, are reported post-COVID-19.
- COVID-19-induced coagulopathy, an immunothrombotic state, is associated with thromboembolic and hemorrhagic events.
Purpose of the Study:
- To review available evidence on post-acute COVID-19 hematological complications.
- To highlight the role of hematologists in managing long COVID-19.
- To emphasize the importance of laboratory monitoring for timely intervention.
Main Methods:
- Literature review of studies on post-COVID-19 hematological complications.
- Synthesis of evidence on COVID-19-induced coagulopathy and thrombocytopenia.
- Discussion of the multidisciplinary approach in long COVID-19 management.
Main Results:
- Post-COVID-19 hematological disorders are a significant concern.
- Late-onset thrombocytopenia, linked to immune dysregulation, is a rare manifestation.
- Close laboratory monitoring is crucial for identifying and managing hematological abnormalities.
Conclusions:
- Hematological complications are an important aspect of long COVID-19.
- Hematologists are essential in the multidisciplinary care of patients with post-COVID-19 hematological issues.
- Timely laboratory assessment and supportive care are vital for managing these conditions.
Abstract:
Coronavirus disease 19 (COVID-19) is considered a multisystemic disease. Several studies have reported persistent symptoms or late-onset complications after acute COVID-19, including post-COVID-19 hematological disorders. COVID-19-induced coagulopathy, an immunothrombotic state, has been linked to thromboembolic and hemorrhagic events. Late-onset thrombocytopenia related to immune system dysregulation has also been reported as a rare manifestation post COVID-19. Close monitoring of laboratory dynamics is considered essential to identify timely abnormal values that need further investigation, providing supportive care whenever indicated. The role of hematologists is essential in terms of the multidisciplinary approach of long COVID-19. This review summarizes all the available evidence on post-acute COVID-19 hematological complications.
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