Related Experiment Video
Updated: Oct 15, 2025
14:58
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
9.9K
Awake Microsurgical Resection for Optochiasmatic Cavernous Malformation
Sebastián Aníbal Alejandro1, Juan Leonardo Serrato-Avila1, Samantha Lorena Paganelli1
1Department of Neurosurgery, Universidade Federal de Sao Paulo, São Paulo-SP, Brazil.
World Neurosurgery
|October 23, 2021
Summary
Optochiasmatic cavernous malformations (CM) can cause vision loss. Microsurgical resection offers a successful treatment option for these rare brain lesions, leading to full patient recovery.
Area of Science:
- Neuroscience
- Neurosurgery
- Ophthalmology
Background:
- Cavernous malformations (CM) are vascular malformations affecting 0.5% of the population.
- Optochiasmatic CMs, though rare, present with significant visual disturbances and neurological symptoms.
Observation:
- A 39-year-old woman with a history of hemorrhagic optochiasmatic CM experienced progressive vision loss.
- Initial treatment with propranolol and microsurgical resection in 2016 provided partial relief.
Findings:
- The patient underwent a second sequential microsurgical resection due to worsening vision and new contralateral symptoms.
- Postoperative MRI confirmed complete resection of the CM, with the patient achieving full visual recovery.
Implications:
- Microsurgical resection is a viable and effective treatment for optochiasmatic CMs causing visual impairment.
- Awake craniotomy allows for safe monitoring of critical neural structures during surgery.
- Complete resection of CMs can lead to significant neurological and visual recovery.
