Related Experiment Video
Updated: Oct 15, 2025

Characterizing Extracellular Vesicles from Biological Fluids
Published on: February 28, 2025
Blood derived extracellular vesicles as regenerative medicine therapeutics
Candice de Boer1, Neil Hamer Davies1
1Cardiovascular Research Unit, Division of Cardiothoracic Surgery, University of Cape Town, Observatory, South Africa.
Abstract:
The regenerative promise of nanosized extracellular vesicles (EVs) secreted by cells is widely explored. Recently, the capacity of EVs purified from blood to elicit regenerative effect has begun to be evaluated. Blood might be a readily available source of EVs, avoiding need for extensive cell culturing, but there are specific issues that complicate use of the biofluid in this area. We assess the evidence for blood containing regenerative material, progress made towards delivering blood derived EVs as regenerative therapeutics, difficulties that relate to the complexity of blood and the promise of hydrogel-based delivery of EVs.
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