Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

175
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
175
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

1.5K
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
1.5K
Heart Failure Drugs: β-Blockers01:22

Heart Failure Drugs: β-Blockers

481
β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation,...
481
Dysrhythmias I: Introduction01:15

Dysrhythmias I: Introduction

230
Dysrhythmias refers to abnormalities in the heart's rhythm. They result from disruptions in the heart's electrical conduction system, which includes the sinoatrial(SA)node, atrioventricular(AV) node, the bundle of His, bundle branches, and Purkinje fibers.Definition and PathophysiologyDysrhythmias result from disorders of impulse formation, impulse conduction, or both. The heart contains specialized cells in the sinoatrial node, atrioventricular node, and the bundle of His and Purkinje fibers...
230
Dysrhythmias III: Characteristics of Dysrhythmias01:29

Dysrhythmias III: Characteristics of Dysrhythmias

164
Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per...
164
Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers01:24

Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers

1.0K
Adrenergic stimulation generally impacts cardiac rate and rhythm. Specifically, stimulation of the β-adrenoceptors triggers an increase in intracellular calcium ion influx and pacemaker currents, which may cause arrhythmias. Catecholamines like adrenaline also demonstrate β2-adrenoceptor-mediated hypokalemia, impacting cardiac action potential and disrupting the normal cardiac rhythm. Class II antiarrhythmic drugs are β-adrenoceptor antagonists or β-blockers, which...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ablating Misconceptions to Prevent Failure of Interpretation: Revisiting the CLAPHAF Study.

Journal of cardiovascular electrophysiology·2025
Same author

Periprocedural Risk Factors for Early Incident Acute Heart Failure After Catheter Ablation of Atrial Fibrillation: Findings From the CLAPHAF Study.

Journal of cardiovascular electrophysiology·2025
Same author

Very slow atrioventricular nodal reentry masquerading as junctional rhythm: Diagnostic challenges and mechanistic insights.

Heart rhythm·2025
Same author

It's electrophysiology, not electrophotography: Location and ablation of accessory pathways.

Heart rhythm·2025
Same author

Video-assisted direct leadless pacemaker implantation during open heart valve surgery.

HeartRhythm case reports·2024
Same author

Safety and efficacy of same-day discharge for premature ventricular complex ablations.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2024

Related Experiment Video

Updated: Oct 15, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.6K

Bilateral Bundle Branch Block.

Jasen L Gilge1, Benzy J Padanilam1

  • 1St Vincent Hospital, 8333 Naab Road, Suite 400, Indianapolis, IN 46260, USA.

Cardiac Electrophysiology Clinics
|October 25, 2021
PubMed
Summary

Bilateral bundle branch block (BBBB) is an uncommon heart condition with features of both left and right bundle branch blocks. This underrecognized disorder may increase cardiovascular risks and benefit from cardiac resynchronization therapy.

Keywords:
Bilateral bundle branch blockBundle branch blockConduction system disorderLeft bundle branch blockRight bundle branch block

More Related Videos

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

1.8K
Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
07:06

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury

Published on: March 21, 2025

784

Related Experiment Videos

Last Updated: Oct 15, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.6K
Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

1.8K
Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
07:06

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury

Published on: March 21, 2025

784

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Conduction

Background:

  • Left bundle branch block (LBBB) and right bundle branch block (RBBB) are well-documented conduction abnormalities.
  • A less common, potentially underrecognized entity, bilateral bundle branch block (BBBB), may present with overlapping features.

Purpose of the Study:

  • To define the characteristics of bilateral bundle branch block (BBBB).
  • To explore the potential clinical implications and management strategies for BBBB.

Main Methods:

  • Analysis of electrocardiographic (ECG) patterns.
  • Review of clinical features and outcomes in patients with BBBB.

Main Results:

  • Bilateral bundle branch block (BBBB) is identified by an RBBB pattern in lead V1 and an LBBB pattern in leads I and aVL.
  • This unique conduction disorder is associated with an increased risk of adverse cardiovascular events.

Conclusions:

  • Bilateral bundle branch block (BBBB) represents a distinct entity within bundle branch conduction disorders.
  • Patients with BBBB may represent a specific population that could benefit from cardiac resynchronization therapy.