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Is there a link between headache and cognitive disorders? A systematic review
J Devianne1, J Mawet2, J Hugon1
1InsermU1144, université de Paris, Paris, France; Centre de Neurologie Cognitive/CMRR Paris Nord Île-de-France, Lariboisière Fernand-Widal hospital, université de Paris, GHU AP-HP Nord, Paris, France.
Revue Neurologique
|October 25, 2021
Summary
Headaches remain common in older adults, even with cognitive decline. Research on the headache-cognitive decline link is limited, highlighting a need for more studies to understand mechanisms and improve treatment.
Area of Science:
- Neurology
- Geriatrics
- Cognitive Science
Background:
- Headaches are prevalent in the elderly, often co-occurring with cognitive decline.
- The relationship between headaches and cognitive decline is poorly understood and underdiagnosed.
Purpose of the Study:
- To conduct a comprehensive review of existing literature on the association between headaches and cognitive decline.
- To synthesize current data on this under-explored topic.
Main Methods:
- Systematic literature review of studies on headaches and neurocognitive disorders.
- Inclusion of all headache types and degenerative neurological conditions.
Main Results:
- Only nine studies have investigated the headache-cognitive decline link.
- Methodological variability was observed across studies.
- Familial Alzheimer's Disease studies showed higher headache prevalence in mutation carriers.
Conclusions:
- The association between headaches and cognitive decline requires further investigation.
- Future research should focus on pathophysiological mechanisms.
- Improved understanding may lead to better treatments for these headaches.
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