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Related Concept Videos

Temperature Measurement Sites01:14

Temperature Measurement Sites

2.4K
A thermometer measures body temperature. The common sites for measuring body temperature are the oral cavity, axillary region, temporal artery, and skin surface, such as the forehead, abdomen, and axilla. True core body temperature is assessed in the rectum, tympanic membrane, pulmonary artery, esophagus, and urinary bladder.
Oral: When assessing oral temperature, the thermometer tip should be placed under the tongue in the posterior sublingual pocket. It offers accurate readings and can be...
2.4K
Thermometers and Temperature Scales01:22

Thermometers and Temperature Scales

6.2K
Any physical property that depends consistently and reproducibly on temperature can be used as the basis of a thermometer. For example, volume increases with temperature for most substances. This property is the basis for the common alcohol thermometer and the original mercury thermometers. Other properties used to measure temperature include electrical resistance, color, and the emission of infrared radiation.
As many physical properties depend on temperature, the variety of thermometers is...
6.2K
Thermosensation01:43

Thermosensation

32.3K
Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
32.3K
Gas Thermometers and the Kelvin Scale01:22

Gas Thermometers and the Kelvin Scale

5.2K
The definition of temperature in terms of molecular motion suggests that there should be a lowest possible temperature, where the average kinetic energy of molecules is zero (or the minimum allowed by quantum mechanics). Experiments confirm the existence of such a temperature, called absolute zero. An absolute temperature scale is one whose zero point is absolute zero. Such scales are convenient in science because several physical quantities, such as the volume of an ideal gas, are directly...
5.2K
Equipments Used to Measure Body Temperature01:13

Equipments Used to Measure Body Temperature

1.4K
Body temperature can be assessed using various devices and measured in Celsius or Fahrenheit.
Glass-bulb Thermometer:
Glass-bulb thermometers are hollow glass tubes with a bulb tip containing liquid such as ethanol or mercury. Historically, glass bulb mercury thermometers were the standard device to measure body temperature. Today, mercury thermometers are prohibited in many countries due to the hazardous effects of mercury and the risk of exposure if the glass bulb breaks. In general,...
1.4K
Body Temperature01:25

Body Temperature

3.4K
The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
3.4K

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Related Experiment Video

Updated: Oct 15, 2025

Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping
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Fiber Optic Distributed Sensors for High-resolution Temperature Field Mapping

Published on: November 7, 2016

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Are TREK Channels Temperature Sensors?

Lola Rueda-Ruzafa1,2, Salvador Herrera-Pérez1,3, Ana Campos-Ríos1,2

  • 1CINBIO, Laboratory of Neuroscience, University of Vigo, Vigo, Spain.

Frontiers in Cellular Neuroscience
|October 25, 2021
PubMed
Summary
This summary is machine-generated.

Electrophysiological studies often use room temperature, not body temperature, for ion channel research. This review highlights TREK subfamily potassium channels

Keywords:
DRGTREK channelsnodose ganglionpotassium channelstemperature sensors

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Area of Science:

  • Neuroscience
  • Biophysics
  • Physiology

Background:

  • Human core body temperature (36.5–37.5°C) differs significantly from typical electrophysiological study temperatures (22–24°C).
  • This temperature discrepancy raises questions about the physiological relevance of ion channel behavior observed in vitro.
  • Temperature profoundly influences biochemical reactions, protein conformation, and cellular processes, including neuronal function.

Purpose of the Study:

  • To investigate the role of TREK subfamily potassium channels in thermal sensitivity transduction.
  • To emphasize the importance of studying ion channels at physiologically relevant temperatures.

Main Methods:

  • Literature review of electrophysiological studies on ion channels.
  • Analysis of studies examining temperature effects on neuronal and ion channel behavior.
  • Focus on TREK subfamily potassium channels and two-pore domain channels.

Main Results:

  • Many ion channels and neurons exhibit altered behavior at different temperatures.
  • Temperature significantly impacts the kinetics of chemical reactions and protein conformational changes.
  • TREK channels are crucial for thermal sensitivity in various cell types.

Conclusions:

  • Studying ion channels at room temperature may not accurately reflect their in vivo function.
  • TREK subfamily potassium channels are key players in cellular thermosensation.
  • Further research at physiological temperatures is needed to understand neuronal function and disease.