Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

History of Microbiology01:28

History of Microbiology

5.9K
Microbiology, a scientific field dedicated to the study of microorganisms, has undergone profound development since its inception in the 17th century. Its history is marked by key discoveries and technological advancements that have shaped our understanding of life at the microscopic level and transformed medicine, agriculture, and industry.Early Foundations of MicrobiologyThe early foundations of microbiology were built on groundbreaking observations and the development of pioneering...
5.9K
Infection01:20

Infection

9.1K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
9.1K
Viral Recombination00:57

Viral Recombination

24.0K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
24.0K
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

253
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
253
Viral Mutations00:36

Viral Mutations

34.9K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
34.9K
Introduction to Epidemiology01:26

Introduction to Epidemiology

1.1K
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Optimized Heart Failure Triaging Protocol to Reduce Avoidable Hospitalizations and Total Costs of Care.

NEJM catalyst innovations in care delivery·2026
Same author

The Ideal Trauma Transport Modality: Helicopter or Ground Ambulance? A Systematic Review and Meta-analysis.

Journal of emergencies, trauma, and shock·2026
Same author

Clinician and simulated patient perspectives on ambient AI scribes in psychiatric consultations: a qualitative study.

Frontiers in psychiatry·2026
Same author

Autoimmune Encephalitis Masquerading As Acute Psychosis: A Cause of Delayed Treatment.

Cureus·2026
Same author

Midodrine for Sepsis Treatment and Early Vasopressor Weaning (MID-STEP): protocol for a pragmatic randomised clinical trial.

BMJ open·2026
Same author

A Rare Case of Semaglutide-Associated Small Bowel Obstruction Complicated by Acute Kidney Injury Requiring Dialysis.

Cureus·2026

Related Experiment Video

Updated: Oct 15, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.5K

Pandemics Throughout the History.

Shrikanth Sampath1, Anwar Khedr2,3, Shahraz Qamar4

  • 1Cardiovascular Medicine, Mayo Clinic, Rochester, USA.

Cureus
|October 25, 2021
PubMed
Summary

Pandemics like COVID-19 have caused global distress, but historical pandemics also spurred scientific advances. Understanding pandemic emergence is key for future preparedness and preventing widespread impact.

Keywords:
choleraebola virusinfluenza pandemicspandemicsplaguesars

More Related Videos

Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

33.3K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.3K

Related Experiment Videos

Last Updated: Oct 15, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.5K
Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

33.3K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.3K

Area of Science:

  • Epidemiology
  • Public Health
  • History of Medicine

Background:

  • The COVID-19 pandemic has caused unprecedented global disruption for over a year.
  • Deadly pandemics, including the plague, Spanish Flu, HIV, and Ebola, have historically caused significant mortality and societal upheaval.
  • These historical events, despite their devastation, have sometimes led to crucial scientific discoveries.

Purpose of the Study:

  • To review historical pandemics and their impact.
  • To understand the mechanisms behind pandemic emergence.
  • To inform clinicians and researchers about critical historical data.

Main Methods:

  • This is a review article.
  • It synthesizes information from historical records of major pandemics.
  • It focuses on the emergence, impact, and lessons learned from past outbreaks.

Main Results:

  • Pandemics have consistently caused widespread death, political instability, and psychosocial burdens throughout history.
  • Historical pandemics have occasionally driven significant scientific and medical progress.
  • Understanding pandemic emergence is vital for effective control and prevention strategies.

Conclusions:

  • Historical pandemics offer critical insights into managing current and future global health crises.
  • Improved pandemic preparedness by public health agencies is essential.
  • Knowledge of past pandemics is crucial for clinicians and researchers to mitigate future threats.