Cardiac Resynchronization Therapy in Cardiogenic Shock: A Case-Based Discussion
Francisco J Somoza-Cano1, Juan F Toledo2, Ramses Amaya-Handal3
1Internal Medicine, St. Vincent Charity Medical Center, Cleveland, USA.
Insights
Cardiac resynchronization therapy (CRT) can improve left ventricular ejection fraction (LVEF) in acute heart failure. This case study shows CRT as a viable option for cardiogenic shock with a wide QRS.
Area of Science:
- Cardiology
- Heart Failure Management
Background:
- Cardiac resynchronization therapy (CRT) is established for heart failure, but its role in acute settings is debated.
- Current guidelines support CRT for chronic heart failure, yet evidence in acute heart failure syndromes (AHFSs) is limited.
Observation:
- A 55-year-old male with alcohol-induced cardiomyopathy presented with new left bundle branch block, QRS duration of 154 ms, and cardiogenic shock (CS).
- Optimal medical management failed to improve the patient's condition.
Findings:
- CRT was implemented as a last resort, leading to a satisfactory clinical course and improved left ventricular ejection fraction (LVEF).
- At four-month follow-up, the patient demonstrated further LVEF augmentation, improved functional class, and no recurrent acute heart failure events.
Implications:
- This case suggests CRT may be a potential therapeutic option for cardiogenic shock patients with a wide QRS.
- Further prospective trials are needed to clarify the utility of CRT in acute heart failure syndromes (AHFSs).
Abstract:
Cardiac resynchronization therapy (CRT) has consistently proven its capability to improve the left ventricular ejection fraction (LVEF). The benefits and indications for this therapy have been elucidated in current heart failure guidelines. However, it remains a topic of discussion if there is a role for it in acute heart failure syndromes (AHFSs). We present the case of a 55-year-old male with a medical history of alcohol-induced cardiomyopathy presenting with a new left bundle branch block, a widened QRS (154 ms), and cardiogenic shock (CS). After a lack of improvement with optimal medical management, CRT was used as a last resort. After implantation, the patient had a satisfactory clinical course and the LVEF improved. At the four-month follow-up, he underwent an outpatient transthoracic echocardiogram with further augmentation of his LVEF, improvement of his functional class, and no reported acute heart failure events. This case illustrates a potential therapeutic option for CS with a widened QRS. Prospective trials should include AHFSs to clarify the utility of CRT in this patient population.
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