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A case report: symptomatic pericarditis post-COVID-19 vaccination

Sarah Ashaari1, Hafiz Ahmed Sohaib1, Kenneth Bolger1

  • 1Department of Medicine, Tipperary University Hospital, Health Service Executive (HSE), Clonmel, Co. Tipperary E91 VY40, Ireland.

European Heart Journal. Case Reports
|October 25, 2021
PubMed

Insights

Pericarditis is a rare side effect following the first dose of the Pfizer-BioNTech COVID-19 vaccine. While rare, the benefits of COVID-19 vaccination outweigh potential risks.

Area of Science:

  • Cardiology
  • Vaccinology
  • Infectious Diseases

Background:

  • The COVID-19 pandemic spurred rapid vaccine development.
  • The CDC noted an increase in myopericarditis post-COVID-19 vaccination.
  • Post-vaccination myopericarditis is an infrequent side effect.

Observation:

  • A patient developed pericarditis 7 days after their first Pfizer-BioNTech COVID-19 vaccine dose.
  • Symptoms included typical pericarditis signs with ECG and echocardiogram changes.
  • Investigations ruled out other causes for the patient's condition.

Findings:

  • The case presented is pericarditis after the first dose of the Pfizer-BioNTech COVID-19 vaccine.
  • The patient experienced symptomatic relief with NSAIDs.
  • Literature reports of post-vaccination pericarditis are limited.

Implications:

  • While rare, pericarditis is a potential side effect of COVID-19 vaccination.
  • The benefits of COVID-19 vaccination continue to outweigh the risks.
  • Further research is needed to establish causality due to limited case numbers.
Abstract

Keywords:
COVID-19Case reportMyopericarditisPericarditisVaccine

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