Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements
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Updated: Oct 15, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Steven A Muller1, Helen L Leavis2, Karim Taha1
1Department of Cardiology, Division Heart and Lung, University Medical Center Utrecht, Utrecht, the Netherlands.
Abstract:
We present a young patient who had to undergo 5 mitral valve replacements (MVR) because of a repetitive immune-mediated noninfectious endocarditis. The patient was treated with multiple anti-inflammatory drugs and high-dose prednisone. After the fifth MVR, the patient remained in stable condition using Anakinra after 22 months of follow-up. (Level of Difficulty: Advanced.).
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