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Updated: Oct 15, 2025

In vivo Evaluation of Mucociliary Clearance in Mice
Published on: December 18, 2020
The relationship between Covid-19 and mucociliary clearance
Mehmet Erkan Kahraman1, Fatih Yüksel1, Yaşar Özbuğday1
1Department of Otolaryngology, Konya City Hospital, Konya, Turkey.
Background:
The effect of Covid-19 infection on nasal mucociliary clearance (MCC) is unknown.
Aims/Objectives:
The aim of this study is to investigate the relationship between Covid-19 and nasal MCC in terms of smoking, Covid-19 symptoms and treatment.
Methods:
Thirty-six patients who were hospitalized in the pandemic ward due to Covid-19 and 36 volunteers (Covid-19 negative test result) who presented to the otolaryngology outpatient clinic with non-nasal symptoms were included in this study. The Saccharin test was performed in both groups to evaluate nasal MCC.
Results:
The patients and control groups were not significantly different in terms of age and gender. The nasal MCC time was significantly higher in the patient group compared to the control group (19.18 ± 10.84 min and 13.78 ± 8.18 min, p = .003).
Conclusions And Significance:
In this study, we found that Covid-19 prolonged nasal MCC time regardless of age. We suggest that corticosteroids should be included in the treatment of Covid-19, both with its symptom reduction and its positive effect on MCC duration.
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