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Risk Factors of Enterostomy Infection Caused by Bacterial Infection through Mathematical Modelling-Based Information
Jing Li1, Xiaoyu Liu1, Jun Chen1
1Gastrointestinal Surgery, Chongqing University Cancer Hospital, No. 181 Hanyu Road, Shapingba District, Chongqing 400030, China.
Objective:
The study aimed to explore the risk factors of infections after enterostomy through the information data analysis method based on a mathematical model.
Methods:
156 cases of enterostomy patients admitted to the hospital were retrospectively selected as the study subjects and were divided into the infection group (17 cases) and normal group (139 cases) according to whether they were complicated with infections. Then, the factors of infection and related indexes before and after surgery were analyzed, and the data of the whole hospital were estimated by mathematical modelling.
Results:
The length of hospital stay in the infection group was 21 ± 11.2 days, which is longer than 10.1 ± 7.1 days in the normal group (P < 0.05). The incidence of anastomotic fistula in the infection group was 14%, which is higher than 2% in the normal group. The mortality rate of infection group (44%) was higher than that of normal group (5%). In the infection group, the incidence of single-cavity stoma (69%) was higher than that of double-cavity stoma (31%), the nosocomial infection rate (11%) was significantly higher compared with out of hospital (2%), and there were significant differences (P < 0.05).
Conclusions:
Patients with malnutrition and hypoproteinemia before enterostomy, the use of gastric tube and ventilator in the treatment, single lumen stomy in the operation, and the occurrence of anastomotic fistula were more likely to have concurrent infections.
Insights
Enterostomy infections are linked to malnutrition, pre-existing hypoproteinemia, and specific surgical factors like single lumen stoma. These infections increase hospital stay, anastomotic fistula rates, and mortality.
Area of Science:
- Medical research
- Surgical outcomes
- Infectious disease epidemiology
Background:
- Enterostomy is a surgical procedure creating an artificial opening for waste elimination.
- Post-enterostomy infections pose significant risks to patient recovery and outcomes.
- Identifying risk factors is crucial for infection prevention and management strategies.
Purpose of the Study:
- To investigate the risk factors associated with infections following enterostomy.
- To analyze patient data and utilize mathematical modeling for risk assessment.
Main Methods:
- Retrospective analysis of 156 enterostomy patients.
- Division into infection (17 cases) and normal (139 cases) groups.
- Mathematical modeling to estimate hospital-wide infection data.
Main Results:
- Infection group had longer hospital stays (21 vs. 10.1 days) and higher anastomotic fistula rates (14% vs. 2%).
- Mortality was significantly higher in the infection group (44% vs. 5%).
- Single-cavity stomas (69%) and nosocomial infections (11%) were more prevalent in the infection group.
Conclusions:
- Malnutrition, hypoproteinemia, gastric tube use, ventilator use, and single lumen stoma are associated with increased infection risk.
- Anastomotic fistula occurrence is a significant indicator of post-enterostomy infection.
- These findings highlight key factors for targeted interventions to reduce enterostomy-related infections.
