Prevalence of congenital cryptorchidism in Estonia

Viljo Kübarsepp1,2, Karin Varik1,2, Heili Varendi3,4

  • 1Department of Surgery, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.

Andrology
|October 26, 2021
PubMed

Insights

Cryptorchidism, or undescended testes, affects 2.1% of newborns in Estonia. Prevalence decreases with age, with most cases resolving spontaneously by six months, indicating lower rates than global averages.

Area of Science:

  • Pediatric Urology
  • Developmental Biology
  • Public Health

Background:

  • Cryptorchidism is a common congenital urogenital malformation with variable prevalence.
  • Understanding regional variations is crucial for public health initiatives.
  • Estonia's specific prevalence data was previously unestablished.

Purpose of the Study:

  • To determine and analyze the prevalence of cryptorchidism in Estonia.
  • To assess spontaneous testicular descent rates in Estonian infants.
  • To compare Estonian cryptorchidism rates with international data.

Main Methods:

  • A cohort of 5014 consecutively born boys at Tartu University Hospital (2012-2015) were examined.
  • Infants diagnosed with cryptorchidism underwent at least six months of follow-up.
  • Prevalence was analyzed based on birth status, gestational age, birth weight, and ethnicity.

Main Results:

  • At birth, 2.1% of boys had cryptorchidism, with higher rates in preterm (11.9%) and low birth weight (16.7%) infants.
  • Spontaneous testicular descent occurred in 61.6% of affected infants by six months.
  • By six months, prevalence was 0.7-1.0% across different birth weight and gestational age groups, with lower rates than previously reported globally.

Conclusions:

  • Estonia exhibits a lower prevalence of cryptorchidism, particularly in full-term infants, compared to Nordic-Baltic countries and worldwide.
  • Early detection and follow-up are essential, as most cases resolve spontaneously.
  • Further research into contributing factors for observed variations may be warranted.
Abstract