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Related Experiment Video

Updated: Oct 15, 2025

Bioinspired Soft Robot with Incorporated Microelectrodes

Bioinspired Soft Robot with Incorporated Microelectrodes

Published on: February 28, 2020

Biomembrane-Functionalized Micromotors: Biocompatible Active Devices for Diverse Biomedical Applications.

Fangyu Zhang¹, Rodolfo Mundaca-Uribe¹, Nelly Askarinam¹

¹Department of Nanoengineering, University of California San Diego, La Jolla, CA, 92093, USA.

Advanced Materials (Deerfield Beach, Fla.)

|October 26, 2021

Summary

This summary is machine-generated.

Synthetic micromotors coated with cell membranes show improved performance in biological settings. This biofunctional approach enhances capabilities for drug delivery, detoxification, and phototherapy in vivo.

Keywords:

cell membranes detoxification drug delivery immunotherapy micromotors phototherapy

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Last Updated: Oct 15, 2025

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Area of Science:

Biomedical Engineering
Nanotechnology
Materials Science

Background:

Synthetic micromotors are being developed for biomedical applications.
Traditional synthetic micromotors face challenges in complex biological environments.
Cell membrane functionalization offers a promising strategy to enhance micromotor capabilities.

Purpose of the Study:

To review proof-of-concept studies on cell membrane-functionalized micromotors.
To analyze the relationship between micromotor structure, cell membrane coating, and performance.
To highlight the advantages of cell membrane functionalization for biomedical applications.

Main Methods:

Review of existing literature on cell membrane-functionalized micromotors.
Analysis of various micromotor designs and cell membrane coating strategies.
Evaluation of performance in complex biological environments and in vivo applications.

Main Results:

Cell membrane-functionalization enhances micromotor propulsion and stability in biological fluids.
These biohybrid micromotors exhibit improved biocompatibility and reduced immune response.
Demonstrated potential in drug delivery, detoxification, immune modulation, and phototherapy.

Conclusions:

Cell membrane-functionalized micromotors overcome limitations of traditional synthetic micromotors.
This approach imparts unique bio-inspired capabilities for advanced biomedical applications.
Further research is expected to accelerate the clinical translation of these advanced micromotors.