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Published on: May 23, 2025
High Risk Percutaneous Coronary Intervention of Left Main Bifurcation Stenosis in a Peritoneal Dialysis Patient
Oliver Bushljetikj1, Biljana Zafirovska Taleska1, Zhan Zimbakov1
1University Clinic of Cardiology, Clinical Centre "Mother Theresa", Skopje, N Macedonia.
Insights
Complex coronary artery disease in dialysis patients poses high risks. This case highlights successful high-risk percutaneous coronary intervention using dual antiplatelet therapy and a specific stenting technique.
Area of Science:
- Cardiology
- Nephrology
Background:
- Complex coronary artery disease (CAD) is a major cause of mortality in end-stage renal disease (ESRD) patients.
- Patients with ESRD, particularly those on peritoneal dialysis, are often excluded from clinical trials, limiting treatment data.
Observation:
- A case report of a patient on peritoneal dialysis with complex left main bifurcation stenosis.
- The patient received dual antiplatelet therapy (DAPT) with Prasugrel and acetylsalicylic acid prior to the procedure.
Findings:
- Successful high-risk percutaneous coronary intervention (PCI) was performed using a "double kiss crush" bifurcation stenting technique.
- This approach demonstrates a potential treatment strategy for complex CAD in ESRD patients.
Implications:
- Provides valuable data on managing complex CAD in a high-risk, often underrepresented patient population.
- Contributes to understanding the safety and efficacy of potent DAPT in ESRD patients, balancing ischemia and bleeding risks.
- Advances PCI techniques for challenging coronary anatomies in vulnerable patient groups.
Abstract:
Complex coronary artery disease is the leading cause of death in patients with end-stage renal disease. We report a case of a patient on peritoneal dialysis, preloaded with Prasugrel and acetylsalicylic acid as а potent dual antiplatelet therapy (DAPT). The patient underwent a high-risk percutaneous coronary intervention (PCI) due to bifurcation stenosis of the left main stem branch. A "double kiss crush" bifurcation stenting technique was performed. This case provides additional data about the treatment of this group of patients, a group that is often excluded from randomized control trials, but is frequently encountered in cardiovascular practice. Furthermore, it helps to advance PCI treatment along with exploring the safety of potent DAPT in a group that is susceptible to both ischemia and bleeding, thus presenting a great challenge in the decision for treatment.
Related Concept Videos
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Hemodialysis II: Procedure and Complications
Cardiac Catheterization I: Pre-Procedure Overview
Peritoneal Dialysis III: Nursing Management
Peritoneal Dialysis I: Introduction and Procedure
Cardiac Catheterization III: Left Heart Catheterization

