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Related Experiment Video

Updated: Oct 15, 2025

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Lifestyle considerations in multiple myeloma.

Yael N Shapiro1, Jeffrey M Peppercorn1,2, Andrew J Yee1,2

  • 1Massachusetts General Hospital, Boston, MA, USA.

Blood Cancer Journal
|October 27, 2021
PubMed
Summary

Improving quality of life for multiple myeloma (MM) patients requires supportive care. Healthy lifestyle behaviors like physical activity and diet can enhance physical functioning and psychological well-being during cancer treatment.

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Area of Science:

  • Oncology
  • Supportive Care
  • Lifestyle Medicine

Background:

  • Multiple myeloma (MM) prognosis has improved, leading to longer treatment durations.
  • Patients with MM experience significant symptom burden and reduced quality of life (QOL).
  • There is a growing need for supportive care interventions to optimize QOL and functional status in MM patients.

Purpose of the Study:

  • To review the role of healthy lifestyle behaviors in improving physical functioning and psychological well-being in MM patients.
  • To synthesize current literature on physical activity, weight management, diet, sleep, and substance use in MM.
  • To identify considerations for integrating lifestyle factors into clinical practice and suggest future research directions.

Main Methods:

  • Literature review of studies on lifestyle behaviors (physical activity, diet, weight management, sleep, substance use) in multiple myeloma.
  • Analysis of current clinical practice considerations for lifestyle interventions.
  • Identification of research gaps and future research priorities.

Main Results:

  • Current literature suggests physical activity, weight management, diet, sleep, and substance use impact MM patient QOL and function.
  • Clinical integration requires consideration of MM-specific factors like osteolytic lesions and anemia.
  • Further research is needed to develop MM-specific lifestyle guidelines.

Conclusions:

  • Healthy lifestyle behaviors are crucial for optimizing QOL and functional status in multiple myeloma patients undergoing prolonged therapy.
  • Developing tailored, evidence-based lifestyle guidelines is essential for supportive care in MM.
  • Addressing modifiable lifestyle factors offers a promising avenue for improving patient outcomes in multiple myeloma.