Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neural Memory State Space Models for Medical Image Segmentation.

International journal of neural systems·2024

Same author

Evaluation of morphological features: femtosecond-LASIK flap vs. SMILE cap, and the effects on corneal higher-order aberrations.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2022

Same author

Autophagy facilitates age-related cell apoptosis-a new insight from senile cataract.

Cell death & disease·2022

Same author

Optimized protocol for high-titer lentivirus production and transduction of primary fibroblasts.

Journal of basic microbiology·2021

Same author

Effect of corneal incision features on anterior and posterior corneal astigmatism and higher-order aberrations after cataract surgery.

Acta ophthalmologica·2021

Same author

Evaluation of ocular symptoms and tropism of SARS-CoV-2 in patients confirmed with COVID-19.

Acta ophthalmologica·2020

Same journal

Fermentative iron reduction by a psychrotolerant Clostridium-dominant consortium enriched from Antarctic penguin-impacted soils.

Communications biology·2026

Same journal

Multilayer brain network analysis in mice reveals ketamine-induced reorganization of brain- wide fluctuations and gut-brain axis.

Communications biology·2026

Same journal

Myofiber-specific knockout of TGF-β type I receptors in mice concurrently drives muscle hypertrophy, oxidative metabolism, and absolute force.

Communications biology·2026

Same journal

The coccosphere of the heavy calcifying coccolithophore Coccolithus braarudii provides defense against bacteria.

Communications biology·2026

Same journal

Non-canonical role of Ku80 stabilizes Rab7A to enhance mitolysosome formation and chemotherapy in liver cancer.

Communications biology·2026

Same journal

In vivo tissue clearing with tartrazine and other dye molecules.

Communications biology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Oct 15, 2025

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

Published on: November 30, 2022

Development of deep learning-based detecting systems for pathologic myopia using retinal fundus images.

Li Lu¹, Enliang Zhou², Wangshu Yu¹

¹Department of Ophthalmology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Communications Biology

|October 27, 2021

Summary

This summary is machine-generated.

Deep learning systems can now detect pathological myopia (PM) and related eye lesions using fundus images. This technology offers accurate, efficient screening for widespread myopia control.

More Related Videos

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model

Published on: April 2, 2021

Related Experiment Videos

Last Updated: Oct 15, 2025

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

Published on: November 30, 2022

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model

Monitoring Dynamic Growth of Retinal Vessels in Oxygen-Induced Retinopathy Mouse Model

Published on: April 2, 2021

Area of Science:

Ophthalmology
Artificial Intelligence
Medical Imaging

Background:

Myopia is a global epidemic, with high and pathological myopia (PM) causing significant visual impairment and blindness in China.
Current myopia screening methods are time-consuming and labor-intensive, necessitating automated solutions.

Purpose of the Study:

To design and evaluate deep learning systems for detecting pathological myopia (PM) and myopic macular lesions.
To classify these conditions based on the international META-PM classification system using color fundus images.

Main Methods:

Development of a series of deep learning systems.
Training and validation using color fundus images.
Performance evaluation against the META-PM classification system.

Main Results:

The deep learning systems demonstrated robust performance on both test and external validation datasets.
The system's diagnostic accuracy was comparable to that of general ophthalmologists and retinal specialists.

Conclusions:

Deep learning offers a viable solution for automated detection of pathological myopia and associated lesions.
Widespread adoption of this technology can enable effective, large-scale myopia screening programs.