Cryptococcosis with Tuberculosis: Overlooked Coinfections
Christina S Suresh1, Marilyn M Ninan1, Anand Zachariah2
1Department of Clinical Microbiology, CMC, Vellore, Tamil Nadu, India.
Abstract:
Tuberculosis and cryptococcosis are important opportunistic pathogens causing significant morbidity and mortality in immunocompromised individuals. Concurrent infections of these two agents are rarely reported. We report five cases of culture-proven coinfection of Mycobacterium tuberculosis and Cryptococcus neoformans during inpatient admission at a tertiary care hospital in southern India between 2007 and 2019. Four patients were persons living with HIV infection and one was on immune suppression for chronic renal disease. Maintaining a high degree of clinical suspicion will ensure early diagnosis and appropriate management of coinfections in the immunocompromised individual.
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