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Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation

Jian Hua Chen1, Guo Yao Chen2, Hong Zheng1

  • 1Department of Cardiology, Fujian Provincial Institute of Coronary Disease, Fujian Heart Medical Center, Fujian Medical University Union Hospital, Fuzhou, China.

Frontiers in Cardiovascular Medicine
|October 28, 2021
PubMed

Insights

Atrial high-rate events (AHREs) occurred in 31.5% of pacemaker patients. Age, symptomatic sick sinus syndrome, and atrial pacing percentage predict AHREs.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Permanent pacemaker implantation is common for bradyarrhythmias.
  • Atrial high-rate events (AHREs) are increasingly recognized in pacemaker populations.
  • Predictors and incidence of AHREs require further elucidation.

Purpose of the Study:

  • To determine the incidence of AHREs in patients with dual-chamber pacemakers.
  • To identify independent predictors of AHREs in this cohort.

Main Methods:

  • Prospective study of 289 patients with dual-chamber pacemakers for complete atrioventricular block or symptomatic sick sinus syndrome (SSS).
  • AHREs defined as atrial frequency ≥175 bpm for ≥5 min.
  • 12-month follow-up with multivariate Cox regression analysis.

Main Results:

  • AHREs were detected in 31.5% of patients over 12 months.
  • Independent predictors of AHREs included older patient age (OR=1.041), pacemaker implantation for symptomatic SSS (OR=2.225), and higher percentage of atrial pacing (OR=1.010).

Conclusions:

  • The incidence of AHREs in pacemaker patients is significant (31.5%).
  • Patient age, indication for pacemaker (symptomatic SSS), and atrial pacing burden are key predictors.
  • These findings aid in risk stratification and management of pacemaker patients.

Keywords:
atrial high-rate eventscardiologypacemakerpercentage of atrial pacingsick sinus syndrome

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