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Requirements for human cardiomyocytes
Miao Yu1, Wei Lei1, Jiani Cao2,3,4
1Department of Cardiovascular Surgery of The First Affiliated Hospital & Institute for Cardiovascular Science, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Medical College, Soochow University, Suzhou, China.
Insights
China
Area of Science:
- Biomedical research
- Stem cell biology
Background:
- Human cardiomyocytes are crucial for disease modeling and drug testing.
- Standardized protocols for human cardiomyocyte research are lacking in China.
Purpose of the Study:
- To introduce the first guideline for human cardiomyocytes in China.
- To standardize research and production of human cardiomyocytes.
Main Methods:
- Jointly drafted by experts from the Chinese Society for Stem Cell Research.
- Specifies technical requirements, test methods, and regulations.
Main Results:
- The guideline covers all aspects from production to disposal.
- Aims to normalize human cardiomyocyte research and production.
Conclusions:
- This guideline promotes proper protocols and institutional adoption.
- Accelerates international standardization for human cardiomyocyte applications.
Abstract:
'Requirements for human cardiomyocytes', jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research, is the first guideline for human cardiomyocytes in China. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packing requirements, storage requirements, transportation requirements and waste disposal requirements for human cardiomyocytes, which is designed to normalize and standardize human cardiomyocyte research and production. It was originally released by the China Society for Cell Biology on 9 January 2021. We hope that the publication of this guideline will promote institutional establishment, acceptance and execution of proper protocols, and accelerate the international standardization of human cardiomyocytes for applications.
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