Related Experiment Video
Updated: Aug 15, 2026
10:38
High Yield Purification of Plasmodium falciparum Merozoites For Use in Opsonizing Antibody Assays
Published on: July 17, 2014
Studies of immunoglobulin M and malarial antibodies in Nigerians
The Journal of Tropical Medicine and Hygiene
|February 1, 1978
Abstract:
Measurements of immunoglobulin M, in 111 healthy adult Nigerians have been presented. IgM values ranged between 10 and 518 mg per 100 ml with a mean of 213.2 mg per 100 ml. Using the indirect immunofluorescent antibody test, 53.7 per cent of the 111 symptomless subjects in the study had demonstrable malarial antibodies of titres greater than 10,000. The implications of the observations in a holoendemic malarial zone are briefly discussed.
Related Concept Videos
01:15Transcytosis of IgG
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
01:29Malaria
Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...