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Recent advances of Sterculia gums uses in drug delivery systems
Júlia Samara Ferreira da Silva1, Antônia Carla de Jesus Oliveira1, Mônica Felts de La Roca Soares1
1Quality Control Core of Medicines and Correlates, Pharmaceutical Sciences Department, Federal University of Pernambuco, Recife, PE, Brazil.
Abstract:
Trees of the genus Sterculia produce polysaccharide-rich exudates, such as karaya gum (Sterculia urens), chicha gum (Sterculia striata), and Sterculia foetida gum. These anionic biomaterials are biodegradable, with high viscosity, low toxicity, and gelling properties in aqueous media. According to these properties, they show promising applications as a polymer matrix for use in drug delivery systems. For this application, both the chemically modified and the unmodified polysaccharide are used. This review focuses on analyzing the state of the art of recent studies on the use of Sterculia gums in a variety of pharmaceutical forms, such as tablets, hydrogels, micro/nanoparticles, and mucoadhesive films. Sterculia gums-based delivery systems have potential to be explored for new drug delivery systems.
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