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A Giant Intramedullary Spinal Tumor.
Mohamad Bydon1, Anshit Goyal2, Panagiotis Kerezoudis1
1Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
World Neurosurgery
|October 28, 2021
Summary
This study details a rare, extensive anaplastic glioma of the thoracic spinal cord. The tumor
Area of Science:
- Neurology
- Neurosurgery
- Oncology
Background:
- Intramedullary spinal cord tumors (IMSCTs) represent 2-4% of central nervous system (CNS) tumors.
- Surgical resection with intraoperative neuromonitoring is the primary treatment for IMSCTs, aiming to prevent neurological deficits.
Observation:
- A case of an extensive (7 vertebral levels) anaplastic glioma in the thoracic spinal cord of a 42-year-old male is presented.
- The tumor's characteristics posed challenges for definitive classification under the 2021 World Health Organization Classification of CNS Tumors.
Findings:
- The presented anaplastic glioma exhibited unusual extent and features.
- Diagnostic classification was complicated, highlighting potential limitations in current grading systems for rare spinal cord tumors.
Implications:
- This case underscores the need for further research into the classification and management of rare and complex intramedullary spinal cord tumors.
- Enhanced diagnostic criteria or molecular subtyping may be necessary for accurate characterization and tailored treatment strategies.

