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Updated: Oct 15, 2025

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
Published on: July 16, 2014
Parkinson's disease-dementia in trans LRP10 and GBA variants: Response to deep brain stimulation
Marcella Neri1, Arianna Braccia2, Celeste Panteghini3
1Unit of Medical Genetics, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Abstract:
We report on a patient with Parkinson's disease and dementia who underwent DBS with excellent response in motor features; the genotype is heterozygous for a novel LRP10 variant in trans with a GBA variant. He had a more severe phenotype compared to the father who only carries the LRP10 variant.
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