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Updated: Oct 15, 2025

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Published on: January 24, 2018
Postoperative Complications Following Ankle Arthrodesis in Patients With Hepatitis C: Matched Propensity Score
Pramod N Kamalapathy1, Sean Sequeira1, Dennis Chen1
1Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia.
Background:
Hepatitis C is associated with increased adverse events following surgery. The goals of this study were therefore to evaluate postoperative outcomes in patients with hepatitis C following ankle arthrodesis.
Materials And Methods:
A review of Medicare patients was performed to identify patients who underwent ankle arthrodesis. Patients were then divided into those with a preoperative history of hepatitis C and those who did not and were matched using propensity scores. Outcomes of interest were analyzed using multivariate logistic regression.
Results:
A diagnosis of hepatitis C was associated with a significantly increased risk of myocardial infarction, emergency department visits, and readmission within 90 days following surgery. In addition, hepatitis C is associated with an increased length of stay, cost of hospitalization, and total hospital charge.
Conclusions:
A diagnosis of hepatitis C was associated with a significant increase in hospital resource utilization during the initial inpatient stay and the immediate post-discharge period.Level of Evidence: III.

