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Published on: January 30, 2018
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What are the functional consequences after TBI? The SHEFBIT cohort experience
Rajiv Singh1,2, Jeremy Dawson3, Prof Suzanne Mason1
1School of Health and Related Research (Scharr), Faculty of Medicine, Dentistry and Health, University of Sheffield S1 4DA, Sheffield, United Kingdom.
Brain Injury
|October 29, 2021
Summary
Functional outcome after Traumatic Brain Injury (TBI) shows considerable disability at one year. Identifying predictors like injury severity and alcohol intoxication can help target rehabilitation for high-risk individuals.
Area of Science:
- Neuroscience
- Clinical Neurology
- Public Health
Background:
- Outcomes after Traumatic Brain Injury (TBI) vary due to measurement differences, attrition, and bias.
- Understanding TBI outcomes is crucial for patient/family guidance, service planning, and identifying at-risk individuals.
Purpose of the Study:
- To investigate functional outcomes one year after Traumatic Brain Injury (TBI).
- To identify predictors of functional outcome using a multi-ordinal regression model.
Main Methods:
- A prospective cohort study included 1322 TBI admissions.
- Functional outcome was assessed at one year using the Extended Glasgow Outcome Scale (GOSE) via structured interviews.
Main Results:
- Outcome data at one year was available for 1207 (91.3%) participants.
- 42.9% achieved Good Recovery, but 11.4% experienced decline, with 4.9% mortality.
- Predictors of worse GOSE included TBI severity, assault etiology, CT abnormalities, psychiatric history, and alcohol intoxication.
Conclusions:
- Significant functional disability persists one year post-TBI in a large cohort.
- Identifying high-risk groups based on predictors may enable targeted rehabilitation strategies.
