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Updated: Oct 15, 2025
Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
Cholecystectomy in patients with hematologic malignancies
Camille L Stewart1, Thuy B Tran1, Andrew Nguyen1
1Department of Surgery, City of Hope, Duarte, CA, USA.
Background:
Cholecystectomy in patients with hematologic malignancies remains poorly understood.
Methods:
We retrospectively evaluated patients with hematologic malignancies who underwent cholecystectomy at a single institution.
Results:
Of 313 patients who presented for evaluation of abdominal pain, 64 underwent cholecystectomy for acute cholecystitis (34.4%), gangrenous cholecystitis (21.9%), chronic cholecystitis (23.4%), and cholelithiasis (20%). Most had a history of hematopoietic cell transplantation (62.5%) and/or immunosuppressive medication within 30 days of consultation (82.8%). Ultrasound had a 39% false-negative rate for acute nongangrenous cholecystitis. Operative time was 92 ± 39 min, 7 were performed open, 10 had intraoperative transfusions, and 4 had grade 3+ complications. Intraoperative transfusion was associated with increased postoperative length of stay (p = 0.03). Open procedure, operative time, estimated blood loss, intraoperative transfusion, and complications were not associated with timing of surgery.
Conclusions:
Patients with hematologic malignancies can safely undergo cholecystectomy. Length of postoperative stay for inpatients is associated with intraoperative blood transfusion.
