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Concurrent Improvement Observed in Patient-Reported Burden and Sensor-Collected Medication Use Among Patients
Leanne Kaye1, Rahul Gondalia1, Meredith A Barrett1
1ResMed Science Center, San Francisco, CA, United States.
Frontiers in Digital Health
|October 29, 2021
Summary
Digital health tools improved COPD assessment test (CAT) scores and reduced short-acting beta-agonist (SABA) inhaler use. Patients experienced parallel improvements, with greater benefits observed in those with higher disease burden.
Area of Science:
- Digital health interventions in respiratory medicine.
- Chronic Obstructive Pulmonary Disease (COPD) management and patient-reported outcomes.
Background:
- The COPD Assessment Test (CAT) is a standard 8-item questionnaire for assessing COPD patient burden.
- Digital health platforms with electronic medication monitors (EMMs) track inhaler usage and patient-reported outcomes.
- Understanding the relationship between digital health interventions, CAT scores, and short-acting beta-agonist (SABA) inhaler use is crucial for COPD management.
Purpose of the Study:
- To examine changes in CAT scores and SABA inhaler use among COPD patients using a digital health platform.
- To determine if passively collected SABA usage and CAT scores change in a parallel manner.
- To assess the impact of a digital health program on COPD patient outcomes.
Main Methods:
- A cohort of 611 patients with self-reported COPD enrolled in a digital health program.
- The program provided EMMs for tracking maintenance and SABA inhaler use, alongside a smartphone app for feedback and reminders.
- CAT scores and EMM-recorded SABA inhaler use were assessed at enrollment and 6 months, with changes quantified relative to the minimally important difference (MID).
Main Results:
- At 6 months, mean CAT scores improved by -0.9 points (p < 0.001), and mean SABA use decreased by -0.6 puffs/day (p < 0.001).
- Patients with higher baseline disease burden (CAT ≥ 21) showed greater improvements: CAT scores decreased by -2.0 points (p < 0.001) and SABA use by -0.8 puffs/day (p < 0.001).
- These improvements in CAT scores and SABA use were statistically significant and demonstrated a parallel trend.
Conclusions:
- Enrollment in a digital health program led to significant and parallel improvements in both CAT scores and SABA inhaler use among COPD patients.
- Patients with a higher initial disease burden experienced more substantial positive changes in their health outcomes.
- Digital health platforms show promise for improving COPD management by concurrently addressing patient-reported burden and medication adherence.
Keywords:
COPD assessment testchronic obstructive pulmonary diseasedigital healthelectronic medication monitoringmedication adherenceshort-acting beta-agonistMore Related Videos
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