Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Energy Budgets00:51

Energy Budgets

9.8K
Organisms must balance energy intake with the energy required for growth, maintenance and reproduction. These trade-offs result in a variety of survivorship and reproductive strategies, including semelparity and iteroparity. Semelparous species, like annual plants, have only one reproductive episode in their lifetimes and consequently have short lifespans. Iteroparous species, by contrast, have many reproductive events during their lifetimes but have relatively few offspring. These two...
9.8K
Probability Laws01:49

Probability Laws

42.3K
Overview
42.3K
Life Histories01:29

Life Histories

20.9K
Overview
20.9K
Population Growth00:57

Population Growth

26.1K
Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.
26.1K
Nondisjunction01:21

Nondisjunction

4.2K
Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold...
4.2K
Inclusive Fitness00:57

Inclusive Fitness

36.4K
Most altruistic behavior—in which one animal helps another at a cost to themselves—occurs between relatives. Scientists think these altruistic behaviors evolved because they increase the inclusive fitness of the animal providing help.
36.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

When Do Annuity-Based Payments Help to Address the Affordability Challenge of Funding Advanced Therapies? Insights from a Budget Impact Simulation.

Journal of market access & health policy·2026
Same author

Weighing Parenthood Wishes: A Conjoint Analysis of Criteria to Prioritize Infertile Couples for Publicly Funded Fertility Treatment.

Medical decision making : an international journal of the Society for Medical Decision Making·2025
Same author

Home-based exercise and PHysical activity maintenance interventiOn after livEr traNsplantation: Impact of eXercise intensity (PHOENIX-Liver).

BMJ open sport & exercise medicine·2025
Same author

Behavioural impact of antibiotic stewardship in children in primary care: interviews with GPs and parents.

JAC-antimicrobial resistance·2024
Same author

Cumulative pregnancy rates of two strategies: Day 3 fresh embryo transfer followed by Day 3 or Day 5/6 vitrification and embryo transfer: a randomized controlled trial.

Human reproduction (Oxford, England)·2023
Same author

Economic Evaluation of Medically Assisted Reproduction: A Methodological Systematic Review.

Medical decision making : an international journal of the Society for Medical Decision Making·2023

Related Experiment Video

Updated: Oct 15, 2025

Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes
09:41

Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes

Published on: September 15, 2023

964

Future Offspring Costs in Economic Evaluation.

Evelyn Verbeke1, Jeroen Luyten2

  • 1Leuven Institute for Healthcare Policy, KU Leuven, Leuven, Belgium. evelyn.verbeke@kuleuven.be.

Pharmacoeconomics
|October 29, 2021
PubMed
Summary
This summary is machine-generated.

Future healthcare costs should include offspring impacts, but only for necessary lives. This approach avoids skewed economic evaluations for fertility-affecting interventions and addresses a gap in Health Technology Assessment (HTA).

More Related Videos

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
20:36

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

8.9K
Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
06:11

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

812

Related Experiment Videos

Last Updated: Oct 15, 2025

Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes
09:41

Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes

Published on: September 15, 2023

964
Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling
20:36

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Published on: July 4, 2007

8.9K
Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
06:11

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

812

Area of Science:

  • Health Economics
  • Population Ethics
  • Health Technology Assessment (HTA)

Background:

  • Current economic evaluation guidelines recommend including all future costs.
  • A significant dimension of future costs, related to offspring, is systematically neglected.
  • Healthcare interventions can influence patient fertility and future offspring health, incurring substantial costs.

Purpose of the Study:

  • To highlight the neglect of future offspring costs in economic evaluations.
  • To propose a framework for including relevant future offspring costs in Health Technology Assessment (HTA).
  • To address the ethical and methodological challenges of incorporating these costs.

Main Methods:

  • Analysis of economic evaluation guidelines and their implications for future costs.
  • Application of the population ethics concept of necessitarianism.
  • Distinguishing between costs associated with 'necessary' versus 'potential' future lives.

Main Results:

  • Future offspring costs can be substantial and vary across interventions and demographics.
  • Systematic inclusion of all future offspring costs presents significant methodological problems.
  • Applying necessitarianism allows exclusion of costs from 'potential' lives, avoiding skewed outcomes.

Conclusions:

  • Future generations represent a substantial gap in current Health Technology Assessment (HTA) methodology.
  • The proposed approach using necessitarianism offers a pragmatic way to account for necessary future costs.
  • Further discussion is needed to refine HTA methodology regarding the economic implications for future generations.