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Novel Process for 3D Printing Decellularized Matrices
Published on: January 7, 2019
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[Research progress on three-dimensional printed interbody fusion cage]
Chunyan Gou1,2, Yuting Zhang3, Guohui Nie4
1Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Shenzhen, Guangdong 518055, P.R.China.
Summary
Three-dimensional printing interbody fusion cages offer advancements in spinal fusion surgery for disc diseases. This review summarizes their molding technology, materials, types, and clinical applications, while exploring future research directions.
Area of Science:
- Orthopedic Surgery
- Biomaterials Engineering
- Medical Device Technology
Background:
- Spinal fusion is a common surgical procedure for moderate to severe intervertebral disc diseases.
- Three-dimensional (3D) printing technology is increasingly utilized for interbody fusion cages in spinal fusion surgery.
Purpose of the Study:
- To summarize the research progress of molding technology and materials for 3D printed interbody fusion cages.
- To classify and analyze the advantages and disadvantages of different types of 3D printed interbody fusion cages.
- To review the clinical applications and future research directions of 3D printed interbody fusion cages.
Main Methods:
- Literature review and synthesis of current research on 3D printed interbody fusion cages.
- Classification of cages based on structural layout: solid-porous-solid (SPS), solid-porous-frame (SPF), frame-porous-frame (FPF), and whole porous cage (WPC).
- Analysis of optimization processes, advantages, disadvantages, and clinical applications of each cage type.
Main Results:
- The study categorizes 3D printed interbody fusion cages into five structural types, detailing their characteristics and clinical use.
- An in-depth analysis of the optimization process, benefits, and drawbacks of each cage classification is provided.
- Current research highlights include advancements in molding technology, material science, and coating applications for these devices.
Conclusions:
- 3D printed interbody fusion cages represent a significant advancement in spinal fusion, offering tailored solutions.
- Further research into molding technologies, novel biomaterials, and advanced coating materials is crucial for future development.
- This review provides a comprehensive reference for researchers and clinicians in the field of interbody fusion cage technology.

