Related Experiment Video
Updated: Oct 15, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Prevalence of cardiac involvement in home-based recovered coronavirus disease 2019 (COVID-19) patients: a
Özge Çakmak Karaaslan1, Murat Oğuz Özilhan2, Orhan Maden2
1Department of Cardiology, Cardiology Clinic, Ankara City Hospital, Ankara, Turkey. ozgecakmak2323@gmail.com.
Insights
Many COVID-19 survivors experience cardiac involvement, even with mild symptoms. Cardiovascular magnetic resonance imaging revealed significant heart abnormalities in 71% of patients, indicating widespread issues.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- COVID-19 is linked to cardiac complications like myocarditis and heart failure.
- Limited data exists on cardiovascular effects in mild, home-recovered COVID-19 patients.
Purpose of the Study:
- To assess cardiac involvement prevalence in recovered COVID-19 patients with mild symptoms.
- To identify factors associated with cardiac involvement post-COVID-19.
Main Methods:
- 64 patients with cardiac symptoms post-COVID-19 were analyzed.
- Cardiovascular magnetic resonance (CMR) imaging was used to evaluate cardiac involvement.
- Patients were categorized based on CMR findings.
Main Results:
- 71% (46/64) of patients showed abnormal CMR findings (myocardial/pericardial enhancement).
- Cardiac involvement was independent of age and comorbidities.
- Patients with cardiac involvement had higher C-reactive protein and lower ejection fraction/stroke volume.
Conclusions:
- Significant cardiac involvement occurs in COVID-19 survivors, even with mild initial symptoms.
- Widespread cardiac issues may be present without elevated troponin or severe clinical presentation.
Objective:
Coronavirus disease 2019 (COVID-19) has a risk of cardiac arrhythmia, acute coronary syndrome, heart failure and myocarditis, and the prognosis of COVID-19 has been associated with cardiovascular symptoms. However, there has not been enough information about cardiovascular involvement in patients who had recovered home-based mild symptoms of COVID-19 infection. Therefore, this study evaluates the prevalence of cardiac involvement and associated factors in home-based recovered COVİD-19 patients.
Subject And Methods:
A total of 64 participants who applied to cardiology outpatient clinics with cardiac symptoms after recovering from COVID infection were recorded between April and December 2020. The patients were divided into two according to cardiovascular involvement in the cardiovascular magnetic resonance (CMR) imaging results.
Results:
No significant difference between the two groups regarding age and co-morbidities. Patients with cardiac involvement had higher C-reactive protein compared to without cardiac involvement patients. A total of 46 patients who recently recovered from COVID-19 had abnormal CMR findings such as myocardial late gadolinium enhancement or pericardial enhancement. In addition, the left ventricular ejection fraction and stroke volume were significantly lower in the cardiac involvement patients.
Conclusion:
We demonstrate cardiac involvement in 46 patients (71%) with recent COVID-19, independent of pre-existing conditions. This indicates that there may be widespread cardiac involvement without high troponin values or severe clinical symptoms.
Related Concept Videos
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Acute Coronary Syndrome III: Diagnostic Studies
Myocarditis III: Medical Management
Myocarditis II: Clinical Features and Diagnostic Tests
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy V: Interprofessional Care

