Evaluation of a new frequency-volume chart for children with primary monosymptomatic nocturnal enuresis: a
Jing-Jing Wang1, Dong-Jie Wang1, Hai-Dong Fu1
1Department of Nephrology, TChildren's Hospital of Zhejiang University School of Medicine, National Clinical Research Center of Child Health, Hangzhou, China.
Insights
A modified 3-day weekend frequency-volume chart (FVC) improved compliance and data quality for tracking primary monosymptomatic nocturnal enuresis (PMNE) in children compared to standard diaries.
Area of Science:
- Pediatric Urology
- Continence Management
Background:
- Primary monosymptomatic nocturnal enuresis (PMNE) affects many children.
- Compliance with traditional voiding diaries can be a challenge.
- A modified 3-day weekend frequency-volume chart (FVC) was developed to enhance patient adherence.
Purpose of the Study:
- To evaluate the compliance and validity of a new modified FVC.
- To compare the modified FVC with the International Children's Continence Society (ICCS) recommended voiding diary.
Main Methods:
- 1200 children with PMNE were randomized to use either the modified FVC or the ICCS diary.
- Compliance was assessed via completing index and quality scores.
- Validity was evaluated by comparing subtype classification, micturition parameters, and desmopressin response rates.
Main Results:
- The modified FVC group showed significantly better diurnal completing index and quality scores.
- No significant differences were observed in subtype classification or desmopressin response rates between the groups.
- 469 patients completed the modified FVC, while 447 completed the ICCS diary.
Conclusions:
- The modified FVC is a valid tool for assessing voiding characteristics in children with PMNE.
- It offers a comparable and potentially superior alternative to the ICCS-recommended diary.
- This modified chart presents a practical option for future clinical use in unselected pediatric populations.
Introduction:
To improve compliance with voiding diaries in children with primary monosymptomatic nocturnal enuresis (PMNE), a new modified 3-day weekend frequency-volume chart (FVC) was designed, and the compliance and validity of this modified FVC was evaluated by comparing with the International Children's Continence Society (ICCS) recommended voiding diary.
Methods:
A total of 1200 patients with PMNE were enrolled in the study from 13 centers in China and were randomly assigned to record this modified FVC or the ICCS-recommended voiding diary. The primary outcome measure was the compliance, assessed by comparing the completing index and the quality score of diaries between two groups. The secondary outcome measure was the validity, evaluated by comparing the constituent of subtypes, micturition parameters and response rate to desmopressin.
Results:
Among the 1200 participants enrolled in the study, 447 patients completed the ICCS-recommended voiding diary and 469 completed the modified diary. The diurnal completing index and the quality score of the modified FVC group were better than those of the ICCS group. In addition, there was no significant difference between these two groups in the subtype classification, or in the response rate to desmopressin.
Conclusions:
The modified FVC could be applied to obtain the voiding characteristics of children with PMNE as the ICCS-recommended voiding diary does and offers a reasonable and better choice for children with PMNE from the unselected population in the future.
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