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COVID-19 associated mucormycosis: A Descriptive Multisite Study from India.
Ritesh Gupta1, Jothydev Kesavadev2, Gopika Krishnan2
1Fortis CDOC Hospital, New Delhi, India.
Diabetes & Metabolic Syndrome
|October 30, 2021
Summary
COVID-19 associated mucormycosis (CAM) is a serious fungal infection. This study found that corticosteroid use and diabetes were common in CAM patients, with a 21.7% mortality rate.
Area of Science:
- Infectious Diseases
- Mycology
- Public Health
Background:
- Mucormycosis is a severe fungal infection with high mortality.
- An increasing number of mucormycosis cases are linked to COVID-19.
- Understanding COVID-19 associated mucormycosis (CAM) is crucial.
Purpose of the Study:
- To analyze the clinical profile of patients with COVID-19 associated mucormycosis (CAM).
- To identify risk factors and outcomes in CAM patients in India.
- To provide data for improved management strategies.
Main Methods:
- Multi-center study involving clinicians across India.
- Data collection on COVID-19 treatment, comorbidities, and CAM diagnosis/treatment/prognosis.
- Descriptive analysis of collected clinical data.
Main Results:
- 115 patients diagnosed with CAM.
- All patients received corticosteroids; 85.2% had diabetes (13.9% newly detected).
- Rhino-orbital site was most common; mortality was 21.7%, associated with lung involvement severity.
Conclusions:
- Universal corticosteroid administration was noted in CAM patients.
- High prevalence of diabetes among CAM patients.
- Observed mortality rate was lower than some previously reported data.
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