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Applying the Social-Ecological Approach to Evaluate Diabetes Medication Management in Older People

Ivy O Poon1, Christopher W Ogboe1

  • 1Texas Southern University, College of Pharmacy and Health Sciences, Houston, Texas.

The Senior Care Pharmacist
|October 31, 2021
PubMed

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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