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Related Concept Videos

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Pattern-based Search of Epigenomic Data Using GeNemo
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SigTools: exploratory visualization for genomic signals.

Shohre Masoumi1, Maxwell W Libbrecht1, Kay C Wiese1

  • 1School of Computing Science, Simon Fraser University, Burnaby, British Columbia, Canada.

Bioinformatics (Oxford, England)
|October 31, 2021
PubMed
Summary
This summary is machine-generated.

SigTools is a new R package for visualizing genomic signals, aiding in data exploration and interpretation for genomic studies. It offers plots to understand genomic data characteristics and includes a web application for broader accessibility.

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Area of Science:

  • Genomics
  • Bioinformatics

Background:

  • Genomic sequencing technologies generate vast datasets, including genomic signals like short-read coverage.
  • Understanding genomic signal characteristics is crucial for evaluating genomic study results.

Purpose of the Study:

  • To introduce SigTools, an R package for genomic signal visualization.
  • To facilitate exploration and interpretation of genomic signals for model development.
  • To provide accessible tools for users with varying technical expertise.

Main Methods:

  • Developed an R-based package named SigTools.
  • Included distribution and autocorrelation plots for genomic signal exploration.
  • Incorporated correlation and aggregation plots for genomic signal interpretation.
  • Created a companion web application, SigTools-Shiny, for GUI-based access.

Main Results:

  • SigTools facilitates genomic signal exploration through various plots.
  • SigTools aids in genomic signal interpretation.
  • SigTools-Shiny enhances accessibility for users preferring graphical interfaces.

Conclusions:

  • SigTools provides essential tools for analyzing genomic signals.
  • The package and its web application improve the understanding and utilization of genomic data.
  • SigTools is freely available, promoting wider adoption in genomic research.