Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diversity of Protists I

Diversity of Protists I

Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

An AI-Ready Phosphorylation Meta-Analysis for <i>Saccharomyces cerevisiae</i>.

Journal of proteome research·2026

Same author

The promise of AlphaFold for gene structure annotation.

Nucleic acids research·2026

Same author

Beyond Invariable Sites: Using Evolutionary Stasis to Map Multi-Layered Constraints on the Evolution of Viral and Mammalian Genomes.

bioRxiv : the preprint server for biology·2026

Same author

CAPHEINE, or everything and the kitchen sink: a workflow for automating selection analyses using HyPhy.

bioRxiv : the preprint server for biology·2026

Same author

Ubiquitin-like SUMO protease expansion in rice (Oryza sativa L.).

The plant genome·2026

Same author

Standardizing RNA-seq Analysis of Fungal Pathogens Using BRC-Analytics and Agentic AI: A <i>Candidozyma auris</i> Case Study.

bioRxiv : the preprint server for biology·2026

Same journal

Correction to 'scSuperAnnotator: A platform for benchmarking comparison and visualizing automated cellular annotation methods for scRNA-seq data'.

Nucleic acids research·2026

Same journal

Correction to 'Differentiable partition function calculation for RNA'.

Nucleic acids research·2026

Same journal

Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA.

Nucleic acids research·2026

Same journal

Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation.

Nucleic acids research·2026

Same journal

Multiple forms of protein-protein and DNA binding are exhibited by BrxC from the BREX phage restriction system.

Nucleic acids research·2026

Same journal

Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.

Nucleic acids research·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Oct 15, 2025

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center.

Beatrice Amos¹, Cristina Aurrecoechea², Matthieu Barba³

¹Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.

Nucleic Acids Research

|October 31, 2021

Summary

This summary is machine-generated.

VEuPathDB integrates omics data for over 500 eukaryotic pathogens, vectors, and hosts. This bioinformatics resource empowers researchers with advanced tools for data mining and analysis across diverse organisms and datasets.

More Related Videos

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

Related Experiment Videos

Last Updated: Oct 15, 2025

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

Area of Science:

Bioinformatics
Computational Biology
Genomics

Background:

VEuPathDB (Eukaryotic Pathogen, Vector and Host Informatics Resource) is a merger of VectorBase and EuPathDB projects.
Funded by NIH and Wellcome Trust, it supports over 500 organisms, including invertebrate vectors, eukaryotic pathogens (protists, fungi), and hosts.
It serves as a Bioinformatics Resource Center.

Purpose of the Study:

To provide researchers with access to omics data and bioinformatic analyses for eukaryotic pathogens, vectors, and hosts.
To integrate diverse datasets and analysis tools within a user-friendly graphical interface.
To facilitate comparative analyses across different datasets, data types, and organisms.

Main Methods:

Integration of over 1700 pre-analyzed datasets with associated metadata.
Standardized analysis workflows, including the OrthoMCL algorithm for orthology prediction.
Development of advanced search capabilities, visualizations, and a graphical user interface.
Upgraded infrastructure supporting a Galaxy workspace for private data analysis.

Main Results:

A comprehensive data mining platform supporting over 500 organisms.
Integration of diverse omics data types with advanced search and analysis tools.
Enhanced user access through a new site-wide search and upgraded web interface.
Support for private data analysis via an expanded Galaxy workspace.

Conclusions:

VEuPathDB is a unique, powerful resource for researchers studying eukaryotic pathogens, vectors, and hosts.
The platform facilitates data exploration, comparative analysis, and private data analysis.
Ongoing upgrades aim to enhance cloud-readiness, host-pathogen interaction tools, and interoperability with other resources.