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Related Experiment Video

Updated: Oct 15, 2025

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

Published on: March 6, 2016

Acoustofluidic platforms for particle manipulation.

Jakub Novotny¹, Andreas Lenshof², Thomas Laurell²

¹Institute of Analytical Chemistry, Czech Academy of Sciences, Brno, Czech Republic.

Electrophoresis

|October 31, 2021

Summary

This summary is machine-generated.

Acoustofluidics uses ultrasonic standing waves for contactless manipulation of cells and particles on-chip. Recent studies show acoustic forces are not harmful to cell viability or function.

Keywords:

Acoustics Acoustofluidics Cell manipulation Microfluidics

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Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations

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Last Updated: Oct 15, 2025

Fabrication and Operation of Acoustofluidic Devices Supporting Bulk Acoustic Standing Waves for Sheathless Focusing of Particles

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Published on: March 6, 2016

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Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations

Published on: August 21, 2018

Area of Science:

Biophysics
Microfluidics
Acoustics

Background:

Acoustofluidics integrates acoustics and microfluidics.
It utilizes ultrasonic standing waves (ASWs) for particle manipulation.
Initial concerns about cell damage from acoustic forces have been addressed.

Purpose of the Study:

To review recent applications of acoustofluidics in biomaterial manipulation.
To highlight advancements in cell and particle handling using ASWs.
To summarize findings on the safety of acoustic forces for cells.

Main Methods:

Review of scientific literature published within the last 5 years.
Focus on studies involving acoustofluidic manipulation of biomaterials.
Analysis of cell and particle behavior under ASW exposure.

Main Results:

Acoustofluidics enables precise, contact-less manipulation of cells and particles.
Demonstrated ability to move and spatially localize microparticles based on acoustophysical properties.
Evidence confirms acoustic forces do not negatively impact cell viability, proliferation, or function.

Conclusions:

Acoustofluidics is a powerful tool for on-chip manipulation of biomaterials.
The technology offers safe and effective methods for handling cells and vesicles.
Continued research is expanding the applications of acoustofluidics in life sciences.