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Data-driven comparison of multiple high-dimensional single-cell expression profiles

Daigo Okada1, Jian Hao Cheng2, Cheng Zheng2

  • 1Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Nanbusogo-Kenkyu-To-1, 5F, 53 Syogoin-Kawaramachi, Sakyo-ku, Kyoto, 606-8507, Japan. dokada@genome.med.kyoto-u.ac.jp.

Journal of Human Genetics
|November 1, 2021
PubMed

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...