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Uterine hyperstimulation resulting from intravaginal prostaglandin E2. A case report
The Journal of Reproductive Medicine
|March 1, 1987
Summary
Intravaginal Prostaglandin E2 effectively improves Bishop scores for labor induction. Terbutaline successfully treated hypertonic uterine contractions post-Prostaglandin E2 administration when other methods failed.
Area of Science:
- Obstetrics and Gynecology
- Pharmacology
Background:
- Elective induction of labor is common.
- Prostaglandin E2 is used to ripen the cervix and improve Bishop scores.
Observation:
- A patient developed hypertonic uterine contractions after receiving 5 mg of intravaginal Prostaglandin E2.
- Contractions persisted for five hours.
Findings:
- Sedation and magnesium sulfate were ineffective in managing the hypertonic contractions.
- Subcutaneous terbutaline (0.25 mg) successfully resolved the hypertonic uterine contractions.
Implications:
- This case highlights a potential adverse effect of Prostaglandin E2 in labor induction.
- Terbutaline may be an effective treatment for refractory hypertonic uterine contractions following Prostaglandin E2 administration.