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Is P&T Ready to Add Rapid Cycle Analytics to Formulary?
Diana Altshuler1, Kenny Yu1, John Papadopoulos1
1NYU Langone Health, New York City, NY, USA.
Rapid cycle analytics and real-world evidence optimize medication evaluation for formulary decisions. This approach improves efficiency and reduces clinician time, enhancing patient care and paving the way for AI-driven drug selection.
Area of Science:
- Health Informatics
- Pharmacoeconomics
- Clinical Analytics
Background:
- The Pharmacy and Therapeutics (P&T) Committee manages formulary additions, often requiring extensive manual review of drug monographs and patient charts for medication use evaluations (MUEs).
- Traditional MUE processes consume significant clinical resources and time, potentially delaying critical decisions and impacting patient care.
- Optimizing the medication evaluation process is crucial for efficient healthcare management and formulary decision-making.
Purpose of the Study:
- To evaluate a novel approach using rapid cycle analytics and real-world evidence to enhance the medication evaluation process.
- To improve formulary decision-making while reducing the time burden on clinicians.
- To assess the effectiveness of intravenous acetaminophen (IV APAP) for total hip arthroplasty (THA) and total knee arthroplasty (TKA) procedures.
Main Methods:
- Implemented rapid cycle analytics, a new methodology for evaluating medication value.
- Assessed the effectiveness of IV APAP in THA and TKA patients, correlating it with opioid utilization, length of stay, and post-anesthesia care unit (PACU) time.
- Partnered with an external analytics expert to organize and normalize internal data, utilizing a large external dataset (over 130 million patients) for reference.
Main Results:
- The study successfully demonstrated the value of IV APAP in THA and TKA procedures.
- The rapid cycle analytics approach allowed for a robust and time-efficient assessment of medication effectiveness and value.
- Significant clinical resources were freed up from MUEs, allowing for more direct patient care.
Conclusions:
- The novel approach using rapid cycle analytics and real-world evidence significantly improved the medication evaluation process.
- This data-rich analytical model enhances the depth of assessments and optimizes the allocation of clinical resources.
- This methodology provides a foundation for future real-time formulary and drug selection decisions using Artificial or Augmented Intelligence (AI).
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Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...

