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Recent Advances in Functional Carbon Quantum Dots for Antitumour
Rong Cai1, Long Xiao1, Meixiu Liu1
1Central Laboratory, Zhangjiagang TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, Jiangsu, 215600, People's Republic of China.
International Journal of Nanomedicine
|November 1, 2021
Summary
Carbon quantum dots (CQDs), small nanomaterials with photoluminescent properties, show great promise for cancer treatment. This review covers their preparation, anticancer functions, and future potential in personalized tumor therapy.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Engineering
Background:
- Carbon quantum dots (CQDs) are photoluminescent nanomaterials (<10 nm) with excellent water dispersibility, chemical stability, and biocompatibility.
- Their unique properties make them highly suitable for diverse biomedical applications, particularly in oncology.
Purpose of the Study:
- To review the recent advancements in carbon quantum dots (CQDs) for anticancer applications.
- To cover CQDs' preparation, characterization, and therapeutic potential in tumor treatment.
Main Methods:
- Fabrication of CQDs using "top-down" and "bottom-up" approaches, involving processes like oxidation, carbonization, pyrolysis, and polymerization.
- Characterization of CQDs' physical and optical properties relevant to biomedical applications.
Main Results:
- CQDs exhibit versatile functions including biological imaging, biosensing, drug delivery, gene therapy, and antimicrobial activity.
- These functions enable CQDs' application in various antitumour strategies, such as photothermal ablation.
Conclusions:
- CQDs offer significant potential for developing novel and precise antitumour therapies.
- Further research into CQDs could pave the way for personalized cancer treatment strategies.
