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Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile
Muhammad Usman Shah Syed1, Zunaira Khan2, Arif Zulfiqar3
1Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
Cureus
|November 1, 2021
Summary
Spinal cord injury (SCI) patients frequently exhibit abnormal lipid profiles and electrocardiogram (ECG) changes. Sinus bradycardia was the most common ECG abnormality in SCI patients with dyslipidemia.
Area of Science:
- Cardiology
- Neurology
- Clinical Medicine
Background:
- Spinal cord injury (SCI) can cause autonomic dysfunction, leading to cardiovascular complications.
- Patients with SCI require frequent monitoring for cardiac issues.
- Autonomic nervous system dysfunction is a known complication of SCI.
Purpose of the Study:
- To investigate electrocardiogram (ECG) abnormalities in spinal cord injury (SCI) patients.
- To evaluate the association between lipid profiles and ECG abnormalities in SCI patients.
Main Methods:
- A cross-sectional study involving 58 SCI patients (35 paraplegia, 23 tetraplegia).
- Lipid profile analysis was performed on fasting blood samples.
- Twelve-lead ECGs were recorded multiple times daily for one month and analyzed.
Main Results:
- Abnormal lipid profiles were observed in 47 out of 58 SCI patients.
- Of those with abnormal lipids, 18 had normal ECGs; of those with normal lipids, only one had ECG abnormalities.
- Specific lipid derangements included abnormal cholesterol, low-density lipoproteins, triglycerides, and high-density lipoprotein values.
Conclusions:
- Sinus bradycardia was the most frequent ECG abnormality in SCI patients with dyslipidemia.
- Further research is recommended to confirm these findings and explore the relationship between SCI, lipid profiles, and cardiac function.
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