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Histomorphological Spectrum of Cervical Lesions in a Rural Hospital
Saravanakumari Vijayakumar1, Pammy Sinha1, Durga Krishnamurthy2
1Department of Pathology, Sri Lakshminarayana Institute of Medical Sciences, Pondicherry, IND.
Cureus
|November 1, 2021
Summary
This study analyzed cervical lesions in a rural Indian population, finding most were benign. Excessive bleeding was linked to low-grade squamous intraepithelial lesions (LSIL).
Area of Science:
- Gynecology
- Pathology
- Public Health
Background:
- Cervical diseases encompass infective, inflammatory, and neoplastic conditions.
- Non-neoplastic cervical lesions are common in sexually active women.
- Cervical cancer is a major health concern in India, with limited studies on rural populations.
Purpose of the Study:
- To investigate the histomorphological spectrum of cervical lesions in a rural Indian cohort.
- To identify associations between clinical presentation and pathological diagnoses.
- To understand differences in cervical disease patterns in rural versus urban settings.
Main Methods:
- Retrospective analysis of gynecological lesions over one year.
- Data extraction from case files including clinical history, examination, and pathological diagnosis.
- Statistical analysis using IBM SPSS for Windows version 22.
Main Results:
- 164 women studied, mean age 46.07 years.
- 75.6% presented with excessive bleeding; 27 had squamous metaplasia, 6 had low-grade squamous intraepithelial lesions (LSIL), and 1 had malignancy.
- Squamous metaplasia and dysplasia were significantly associated with final diagnoses like LSIL, high-grade squamous intraepithelial lesions (HSIL), and chronic cervicitis.
Conclusions:
- Rural populations require focused studies on the histomorphological spectrum of cervical lesions, not just knowledge, attitude, and practices.
- Factors like education, parity, hygiene, and socioeconomic status influence cervical disorders.
- The majority of cervical lesions in this rural cohort were benign.
